1.基本情况
赵素娟,中共党员,博士,副教授,就职于beat365平台职业卫生与环境卫生学系。近年来,主持国家自然科学基金2项,安徽省自然科学基金青年基金1项,省高校优秀人才支持计划1项,先后参加多项国家自然科学基金项目和省部级科研项目,发表多篇SCI学术论文。主要研究方向为水体污染和生态毒理学,关注微囊藻毒素的生态毒理学研究,特别是蓝藻水华对水生生物作用的分子机制、危险评价、健康危害及生态毒理学效应。招生专业及方向:环境卫生。联系方式:zsj_700@163.com。
2. 主持与参加科研项目
(1) 国家自然科学基金面上项目,31971521,父代微囊藻毒素暴露致子代斑马鱼神经发育损害的表观遗传机制,2020/01-2023/12, 58万元,在研,主持;
(2)安徽省高校优秀人才支持计划,gxyq2019011, 父代斑马鱼微囊藻毒素暴露通过精子表观遗传改变致子代神经发育损伤的机制研究,2019/01-2020/12, 3万,在研,主持;
(3)国家自然科学基金青年项目,31400455,内质网应激和线粒体通路交联介导微囊藻毒素致斑马鱼雄性生殖细胞凋亡中的作用, 2015/01-2017/12, 25万元,已结题,主持;
(4)安徽省自然科学基金青年项目,1408085QH160,GABA和谷氨酸神经递质在微囊藻毒素诱发斑马鱼神经毒性中的分子作用机制,2014/07-2016/06,7万元,已结题,主持;
3. 代表性论文
(1)Zhao SJ, Yuan CY, Tuo X, Zhou CF, Zhao QH, Shen T*. 2020. MCLR induces dysregulation of calcium homeostasis and endoplasmic reticulum stress resulting in apoptosis in Sertoli cells. Chemosphere. 15; 263:127868.
(2)Zhao SJ, Zhong SZ, Wang F, Wang HH, Xu DX*, Li GY*.2020. Microcystin-LR exposure decreased the fetal weight of mice by disturbance of placental development and ROS-mediated endoplasmic reticulum stress in the placenta. Environ Pollut. 256:113362.
(3)Zhong SZ, Liu Y, Wang F, Wu ZW, Zhao SJ*.2020 Microcystin-LR induced oxidative stress, in flammation, and apoptosis in alveolar type II epithelial cells of ICR mice in vitro. 174:19-25.
(4)Zhao SJ, Sun Hong*, Yan Wei*, Xu Dexiang, Shen Tong. 2018. A proteomic study of the pulmonary injury induced by microcystin-LR in mice. Toxicon. 150:304-314.
(5)Zhao SJ, Liu Y, Wang F, Xu DX*, Xie P*. 2018. N-acetylcysteine protects against microcystin-LR-induced endoplasmic reticulum stress and germ cell apoptosis in zebrafish testes. Chemosphere, 204:463-473.
(6)Yan W, Li L, Li GY, Zhao SJ*. 2017. Microcystin-LR induces changes in the GABA neurotransmitter system of zebrafish. Aquat Toxicol,188:170-176.
(7)袁春阳,谢平,刘颖,赵素娟*,沈彤*.微囊藻毒素-LR 急性呼吸道暴露对小鼠生殖细胞凋亡的影响及其作用机制 2017. 环境与健康杂志, 34(11):961-964.
(8)Zhao SJ, Xie P*, Chen J, Liu LY, Fan HH. 2016. A proteomic study on liver impairment in rat pups induced by maternal microcystin-LR exposure. Environmental Pollution 212: 197-207.
(9)Zhao SJ, Li GY*, Chen J*. 2015. A proteomic analysis of prenatal transfer of microcystin-LR induced neurotoxicity in rat offspring. Journal of Proteomics 114: 197-213.